PD Dr.-Ing. (Dipl. Biol) Katrin Ochsenreither

  • Gebäude 30.44 Bioturm
    Fritz-Haber-Weg 2
    76131 Karlsruhe



Der Schwerpunkt der Arbeitsgruppe liegt auf der Biotechnologie mit Pilzen und der Bearbeitung aller Aspekte von der Medienoptimierung, über Evaluation und Verwendung nachhaltiger Substrate, Prozessentwicklung  und -optimierung für die Produktion von lignocellulytischen Enzymen mit anaeroben Pilzen, Einzellerölen mit verschiedenen Hefestämmen und organischer Säuren mit den filamentösen Schimmelpilzen Aspergillus oryzae und Rhizopus delemar. Auf die Integration molekularbiologischer Arbeitstechniken wird in laufenden Projekten bereits ein stärkeres Gewicht gelegt.


Evaluating the effect of cultivation conditions on palmitoleic acid-rich lipid production by Scheffersomyces segobiensis DSM 27193.
Zhou, X.; Bao, X.; Zhou, J.; Xin, F.; Zhang, W.; Qian, X.; Dong, W.; Jiang, M.; Ochsenreither, K.
2021. Biofuels, bioproducts and biorefining. doi:10.1002/bbb.2286
Global Transcriptome Profile of the Oleaginous Yeast Saitozyma podzolica DSM 27192 Cultivated in Glucose and Xylose.
Aliyu, H.; Gorte, O.; Neumann, A.; Ochsenreither, K.
2021. Journal of Fungi, 7 (9), Art.-Nr.: 758. doi:10.3390/jof7090758
Isolation and Biochemical Characterization of Six Anaerobic Fungal Strains from Zoo Animal Feces.
Stabel, M.; Schweitzer, T.; Haack, K.; Gorenflo, P.; Aliyu, H.; Ochsenreither, K.
2021. Microorganisms, 9 (8), Article: 1655. doi:10.3390/microorganisms9081655
Characterization and Phylogenetic Analysis of a Novel GH43 β-Xylosidase From Neocallimastix californiae.
Stabel, M.; Hagemeister, J.; Heck, Z.; Aliyu, H.; Ochsenreither, K.
2021. Frontiers in Fungal Biology, 2. doi:10.3389/ffunb.2021.692804
Lipase-Catalyzed Production of Sorbitol Laurate in a “2-in-1” Deep Eutectic System: Factors Affecting the Synthesis and Scalability.
Delavault, A.; Opochenska, O.; Laneque, L.; Soergel, H.; Muhle-Goll, C.; Ochsenreither, K.; Syldatk, C.
2021. Molecules, 26 (9), 2759. doi:10.3390/molecules26092759
Co‐production of microbial lipids with valuable chemicals.
Chen, L.; Qian, X.; Zhang, X.; Zhou, X.; Zhou, J.; Dong, W.; Xin, F.; Zhang, W.; Jiang, M.; Ochsenreither, K.
2021. Biofuels, bioproducts and biorefining, Art.-Nr. bbb.2209. doi:10.1002/bbb.2209
Acetate as substrate for l-malic acid production with Aspergillus oryzae DSM 1863.
Kövilein, A.; Umpfenbach, J.; Ochsenreither, K.
2021. Biotechnology for Biofuels, 14 (1), Art.-Nr.: 48. doi:10.1186/s13068-021-01901-5
Microwave-Assisted One-Pot Lipid Extraction and Glycolipid Production from Oleaginous Yeast Saitozyma podzolica in Sugar Alcohol-Based Media.
Delavault, A.; Ochs, K.; Gorte, O.; Syldatk, C.; Durand, E.; Ochsenreither, K.
2021. Molecules (Basel, Switzerland), 26 (2), Art.-Nr. 470. doi:10.3390/molecules26020470
Bioconversion of volatile fatty acids into lipids by the oleaginous yeast Apiotrichum porosum DSM27194.
Qian, X.; Zhou, X.; Chen, L.; Zhang, X.; Xin, F.; Dong, W.; Zhang, W.; Ochsenreither, K.; Jiang, M.
2020. Fuel, 119811. doi:10.1016/j.fuel.2020.119811
Aestipascuomyces dupliciliberans gen. nov, sp. nov., the First Cultured Representative of the Uncultured SK4 Clade from Aoudad Sheep and Alpaca.
Stabel, M.; Hanafy, R. A.; Schweitzer, T.; Greif, M.; Aliyu, H.; Flad, V.; Young, D.; Lebuhn, M.; Elshahed, M. S.; Ochsenreither, K.; Youssef, N. H.
2020. Microorganisms, 8 (11), Article no: 1734. doi:10.3390/microorganisms8111734
Valorization of Crude Glycerol into Citric Acid and Malic Acid by Yarrowia lipolytica.
Qian, X.; Xu, N.; Jing, Y.; Song, M.; Zhou, J.; Dong, W.; Xin, F.; Zhang, W.; Jiang, M.; Ochsenreither, K.
2020. Industrial & engineering chemistry research, A - H. doi:10.1021/acs.iecr.0c01723
Interfacial and Foaming Properties of Tailor-Made Glycolipids—Influence of the Hydrophilic Head Group and Functional Groups in the Hydrophobic Tail.
Hollenbach, R.; Völp, A. R.; Höfert, L.; Rudat, J.; Ochsenreither, K.; Willenbacher, N.; Syldatk, C.
2020. Molecules, 25 (17), 3797. doi:10.3390/molecules25173797
Pulsed Electric Field Treatment Promotes Lipid Extraction on Fresh Oleaginous Yeast Saitozyma podzolica DSM 27192.
Gorte, O.; Nazarova, N.; Papachristou, I.; Wüstner, R.; Leber, K.; Syldatk, C.; Ochsenreither, K.; Frey, W.; Silve, A.
2020. Frontiers in Bioengineering and Biotechnology, 8, Article 575379. doi:10.3389/fbioe.2020.575379
Enzymatic synthesis of glucose monodecanoate in a hydrophobic deep eutectic solvent.
Hollenbach, R.; Ochsenreither, K.; Syldatk, C.
2020. International journal of molecular sciences, 21 (12), Article no: 4342. doi:10.3390/ijms21124342
Optimization of glycolipid synthesis in hydrophilic deep eutectic solvents.
Hollenbach, R.; Bindereif, B.; Van Der Schaaf, U. S.; Ochsenreither, K.; Syldatk, C.
2020. Frontiers in Bioengineering and Biotechnology, 8, Art.-Nr.: 382. doi:10.3389/fbioe.2020.00382
Evaluation of Downstream Processing, Extraction, and Quantification Strategies for Single Cell Oil Produced by the Oleaginous Yeasts Saitozyma podzolica DSM 27192 and Apiotrichum porosum DSM 27194.
Gorte, O.; Hollenbach, R.; Papachristou, I.; Steinweg, C.; Silve, A.; Frey, W.; Syldatk, C.; Ochsenreither, K.
2020. Frontiers in Bioengineering and Biotechnology, 8, Article no: 355. doi:10.3389/fbioe.2020.00355
In silico proteomic analysis provides insights into phylogenomics and plant biomass deconstruction potentials of the Tremelalles.
Aliyu, H.; Gorte, O.; Zhou, X.; Neumann, A.; Ochsenreither, K.
2020. Frontiers in Bioengineering and Biotechnology, 8, Article: 226. doi:10.3389/fbioe.2020.00226
Biotechnological potential and applications of microbial consortia.
Qian, X.; Chen, L.; Sui, Y.; Chen, C.; Zhang, W.; Zhou, J.; Dong, W.; Jiang, M.; Xin, F.; Ochsenreither, K.
2020. Biotechnology advances, 40, Art.Nr. 107500. doi:10.1016/j.biotechadv.2019.107500
Genomic insights into the lifestyles, functional capacities and oleagenicity of members of the fungal family Trichosporonaceae.
Aliyu, H.; Gorte, O.; De Maayer, P.; Neumann, A.; Ochsenreither, K.
2020. Scientific reports, 10, 2780. doi:10.1038/s41598-020-59672-2
Malic acid production from renewables: A review.
Kövilein, A.; Kubisch, C.; Cai, L.; Ochsenreither, K.
2020. Journal of chemical technology & biotechnology, 95 (3), 513–526. doi:10.1002/jctb.6269
Enzymatic glycolipid surfactant synthesis from renewables.
Grüninger, J.; Delavault, A.; Ochsenreither, K.
2019. Process biochemistry, 87, 45–54. doi:10.1016/j.procbio.2019.09.023
Continuous self-provided fermentation for microbial lipids production from acetate by using oleaginous yeasts Cryptococcus podzolicus and Trichosporon porosum.
Qian, X.; Gorte, O.; Chen, L.; Zhang, W.; Dong, W.; Ma, J.; Xin, F.; Jiang, M.; Ochsenreither, K.
2020. Renewable energy, 146, 737–743. doi:10.1016/j.renene.2019.07.013
Co-production of single cell oil and gluconic acid using oleaginous Cryptococcus podzolicus DSM 27192.
Qian, X.; Gorte, O.; Chen, L.; Zhang, W.; Dong, W.; Ma, J.; Jiang, M.; Xin, F.; Ochsenreither, K.
2019. Biotechnology for biofuels, 12 (1), Art. Nr.: 127. doi:10.1186/s13068-019-1469-9
The Complex Way to Sustainability: Petroleum-Based Processes versus Biosynthetic Pathways in the Formation of C4 Chemicals from Syngas.
Stoll, I. K.; Boukis, N.; Neumann, A.; Ochsenreither, K.; Zevaco, T. A.; Sauer, J.
2019. Industrial & engineering chemistry research, 58 (35), 15863–15871. doi:10.1021/acs.iecr.9b01123
Draft Genome Sequence of the Oleaginous Yeast Saitozyma podzolica (syn. Cryptococcus podzolicus) DSM 27192.
Aliyu, H.; Gorte, O.; Neumann, A.; Ochsenreither, K.
2019. Microbiology Resource Announcements, 8 (8), Article: e01676–18. doi:10.1128/MRA.01676-18
Draft Genome Sequence of the Oleaginous Yeast Apiotrichum porosum (syn. Trichosporon porosum) DSM 27194.
Gorte, O.; Aliyu, H.; Neumann, A.; Ochsenreither, K.
2019. Journal of Genomics, 7, 11–13. doi:10.7150/jgen.32210
Integrated Process for the Enzymatic Production of Fatty Acid Sugar Esters Completely Based on Lignocellulosic Substrates.
Siebenhaller, S.; Kirchhoff, J.; Kirschhöfer, F.; Brenner-Weiß, G.; Muhle-Goll, C.; Luy, B.; Haitz, F.; Hahn, T.; Zibek, S.; Syldatk, C.; Ochsenreither, K.
2018. Frontiers in Chemistry, 6, Article: 421. doi:10.3389/fchem.2018.00421
Current status and perspectives of 2-phenylethanol, a natural flavor production through biotechnological process.
Qian, X.; Yan, W.; Zhang, W.; Dong, W.; Ma, J.; Ochsenreither, K.; Xin, F.; Jiang, M.
2019. Critical reviews in biotechnology, 39 (2), 1–14. doi:10.1080/07388551.2018.1530634
FoldX as Protein Engineering Tool: Better Than Random Based Approaches?.
Buß, O.; Rudat, J.; Ochsenreither, K.
2018. Computational and structural biotechnology journal, 16, 25–33. doi:10.1016/j.csbj.2018.01.002
Lipase-Catalyzed Synthesis of Sugar Esters in Honey and Agave Syrup.
Siebenhaller, S.; Gentes, J.; Infantes, A.; Muhle-Goll, C.; Kirschhöfer, F.; Brenner-Weiß, G.; Ochsenreither, K.; Syldatk, C.
2018. Frontiers in Chemistry, 6, Article: 24. doi:10.3389/fchem.2018.00024
Sustainable carbon sources for microbial organic acid production with filamentous fungi.
Dörsam, S.; Fesseler, J.; Gorte, O.; Hahn, T.; Zibek, S.; Syldatk, C.; Ochsenreither, K.
2017. Biotechnology for biofuels, 10 (1), 242. doi:10.1186/s13068-017-0930-x
Evaluation of Pyrolysis Oil as Carbon Source for Fungal Fermentation.
Dörsam, S.; Kirchhoff, J.; Bigalke, M.; Dahmen, N.; Syldatk, C.; Ochsenreither, K.
2016. Frontiers in microbiology, 7, Art.Nr. 2059. doi:10.3389/fmicb.2016.02059
Production strategies and applications of microbial single cell oils.
Ochsenreither, K.; Glück, C.; Stressler, T.; Fischer, L.; Syldatk, C.
2016. Frontiers in microbiology, 7, 1539. doi:10.3389/fmicb.2016.01539
Potentially biocompatible polyacrylamides derived by the Ugi four-component reaction.
Sehlinger, A.; Ochsenreither, K.; Bartnick, N.; Meier, M. A. R.
2015. European polymer journal, 65 (313-324), 313–324. doi:10.1016/j.eurpolymj.2015.01.032
Sequential Mixed Cultures : From Syngas to Malic Acid.
Oswald, F.; Dörsam, S.; Veith, N.; Zwick, M.; Neumann, A.; Ochsenreither, K.; Syldatk, C.
2016. Frontiers in microbiology, 7, 891. doi:10.3389/fmicb.2016.00891
Influence of pH and carbon to nitrogen ratio on mycotoxin production by Alternaria alternata in submerged cultivation.
Brzonkalik, K.; Hümmer, D.; Syldatk, C.; Neumann, A.
2012. AMB Express, 2 (1), ArticleNr. 28. doi:10.1186/2191-0855-2-28
Microbial Production of Value-Added Chemicals from Pyrolysis Oil and Syngas.
Neumann, A.; Dörsam, S.; Oswald, F.; Ochsenreither, K.
2015. Sustainable Production of Bulk Chemicals : Integration of Bio-, Chemo-Resources and Processes. Ed.: M. Xian, 69–105, Springer Netherlands
Process characterization and influence of alternative carbon sources and carbon-to-nitrogen ratio on organic acid production by Aspergillus oryzae DSM 1863.
Ochsenreither, K.; Fischer, C.; Neumann, A.; Syldatk, C.
2014. Applied Microbiology and Biotechnology, 98 (12), 5449–5460. doi:10.1007/s00253-014-5614-x
Characterization of newly isolated oleaginous yeasts - Cryptococcus podzolicus, Trichosporon porosum and pichia segobiensis.
Schulze, I.; Hansen, S.; Großhans, S.; Rudszuck, T.; Ochsenreither, K.; Syldatk, C.; Neumann, A.
2014. AMB Express, 4 (24), 1–10. doi:10.1186/s13568-014-0024-0
Process development for the elucidation of mycotoxin formation in Alternaria alternata.
Brzonkalik, K.; Herrling, T.; Syldatk, C.; Neumann, A.
2011. AMB Express, 1, 27. doi:10.1186/2191-0855-1-27
The influence of different nitrogen and carbon sources on mycotoxin production in Alternaria alternata.
Brzonkalik, K.; Herrling, T.; Syldatk, C.; Neumann, A.
2011. International Journal of Food Microbiology, 147 (2), 120–126. doi:10.1016/j.ijfoodmicro.2011.03.016
Process development for the production of Alternaria toxins in a bioreactor. Dissertation.
Brzonkalik, K.
2011. Karlsruher Institut für Technologie (KIT). doi:10.5445/IR/1000025324

Curriculum Vitae


Wissenschaftlicher Werdegang

seit 2013 Arbeitsgruppenleiterin "Biotechnologie der Pilze" am BLT 2: Technische Biologie, KIT
2012 Post-Doc Aufenthalt bei Prof. H. Huang, PhD an der Nanjing Tech University, Nanjing, China. Forschungsthema: „Produktion von L-Malat mit Aspergillus oryzae)
2006-2008 Wissenschaftliche Mitarbeiterin an der Friedrich-Schiller-University Jena, Lehrstuhl für Allgemeine Mikrobiologie/Hans-Knöll-Institut, Mitglied in der „International Leibniz Research School“. Forschungsthema: “Regulation des sexuellen Kommunikationssystems in Zygomyceten“.
2001-2006 Studium der Biologie (Diplom) an der Ruhruniversität Bochum. Diplomarbeit am Lehrstuhl für Allgemeine und Molekulare Botanik, Prof. Kück. Thema: „Molekulargenetische Analyse von Kreuzungstypproteinen des filamentösen Ascomyceten Sordaria macrospora“



2006-2008 Stipendium der „International Leibniz Research School“ in Jena
2012 Post-Doc Stipendium des Ministeriums für Wissenschaft, Forschung und Kunst Baden-Württemberg


Lehrtätigkeiten und öffentliche Vorträge

Grundvorlesung „Genetik“, Grundpraktikum „Biotechnologie, Teil Enzymtechnik“ für den Bachelor-Studiengang Bioingenieurwesen

Vertiefungsfachvorlesung und Praktikum „Biotechnologie der Pilze“ für den Master-Studiengang Bioingenieurwesen in Vorbereitung

Öffentliche Vorträge im Rahmen der „Langen Nacht der Wissenschaft“, „Thüringen-Tag“ und „Uni für Einsteiger“